Ryan Rampersaud, MD, PhD

Physician
Psychiatry

Ryan Rampersaud, MD, PhD is a child and adolescent psychiatrist in the Division of Child and Adolescent Psychiatry in the UCSF Department of Psychiatry and Behavioral Sciences. Dr. Rampersaud completed his MD and PhD in Microbiology/Immunology at Columbia University, and his psychiatry residency and child and adolescent fellowship at UCSF. Dr. Rampersaud has interests in the treatment of mood disorders and the impact of trauma on mental health. His research focuses on understanding the role of the human gut microbiome in the development of psychiatric disease and biological mechanisms by which early life adversity affects physical and mental health. 

Publications: 

Kynurenine Metabolism is Associated with Antidepressant Response to Selective Serotonin Reuptake Inhibitors.

bioRxiv : the preprint server for biology

Rampersaud R, Suneson K, Wu GWY, Reus VI, Lindqvist D, Ho TC, Meyerhoff DJ, Irwin MR, Wolkowitz OM, Mellon SH, Brundin L

The researcher's guide to selecting biomarkers in mental health studies.

BioEssays : news and reviews in molecular, cellular and developmental biology

Verhoeven JE, Wolkowitz OM, Barr Satz I, Conklin Q, Lamers F, Lavebratt C, Lin J, Lindqvist D, Mayer SE, Melas PA, Milaneschi Y, Picard M, Rampersaud R, Rasgon N, Ridout K, Söderberg Veibäck G, Trumpff C, Tyrka AR, Watson K, Wu GWY, Yang R, Zannas AS, Han LKM, Månsson KNT

Examining putamen resting-state connectivity markers of suicide attempt history in depressed adolescents.

Frontiers in psychiatry

Tymofiyeva O, Ho TC, Connolly CG, Gorrell S, Rampersaud R, Darrow SM, Max JE, Yang TT

Serum brain-derived neurotrophic factor, Val66Met polymorphism and open-label SSRI treatment response in Major Depressive Disorder.

Psychoneuroendocrinology

Smit AJT, Wu GWY, Rampersaud R, Reus VI, Wolkowitz OM, Mellon SH

Circulating cell-free mitochondrial DNA levels and glucocorticoid sensitivity in a cohort of male veterans with and without combat-related PTSD.

Translational psychiatry

Blalock ZN, Wu GWY, Lindqvist D, Trumpff C, Flory JD, Lin J, Reus VI, Rampersaud R, Hammamieh R, Gautam A, SBPBC, Doyle FJ, Marmar CR, Jett M, Yehuda R, Wolkowitz OM, Mellon SH

Shorter telomere length predicts poor antidepressant response and poorer cardiometabolic indices in major depression.

Scientific reports

Rampersaud R, Wu GWY, Reus VI, Lin J, Blackburn EH, Epel ES, Hough CM, Mellon SH, Wolkowitz OM

Molecular signatures of post-traumatic stress disorder in war-zone-exposed veteran and active-duty soldiers.

Cell reports. Medicine

Muhie S, Gautam A, Yang R, Misganaw B, Daigle BJ, Mellon SH, Flory JD, Abu-Amara D, Lee I, Wang K, Rampersaud R, PTSD Systems Biology Consortium, Hood L, Yehuda R, Marmar CR, Wolkowitz OM, Ressler KJ, Doyle FJ, Hammamieh R, Jett M

Dimensions of childhood adversity differentially affect biological aging in major depression.

Translational psychiatry

Rampersaud R, Protsenko E, Yang R, Reus V, Hammamieh R, Wu GWY, Epel E, Jett M, Gautam A, Mellon SH, Wolkowitz OM

"GrimAge," an epigenetic predictor of mortality, is accelerated in major depressive disorder.

Translational psychiatry

Protsenko E, Yang R, Nier B, Reus V, Hammamieh R, Rampersaud R, Wu GWY, Hough CM, Epel E, Prather AA, Jett M, Gautam A, Mellon SH, Wolkowitz OM

Novel Pharmacological Targets for Combat PTSD-Metabolism, Inflammation, The Gut Microbiome, and Mitochondrial Dysfunction.

Military medicine

Bersani FS, Mellon SH, Lindqvist D, Kang JI, Rampersaud R, Somvanshi PR, Doyle FJ, Hammamieh R, Jett M, Yehuda R, Marmar CR, Wolkowitz OM

Environmental pH modulates inerolysin activity via post-binding blockade.

Scientific reports

Rampersaud R, Lewis EL, LaRocca TJ, Ratner AJ

Evidence for a-synuclein prions causing multiple system atrophy in humans with parkinsonism.

Proceedings of the National Academy of Sciences of the United States of America

Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, Grinberg LT, Giles K

Propagation of prions causing synucleinopathies in cultured cells.

Proceedings of the National Academy of Sciences of the United States of America

Woerman AL, St?hr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, S?dhof TC, Giles K, Prusiner SB

Vaginolysin drives epithelial ultrastructural responses to Gardnerella vaginalis.

Infection and immunity

Randis TM, Zaklama J, LaRocca TJ, Los FC, Lewis EL, Desai P, Rampersaud R, Amaral FE, Ratner AJ

Genome Sequence of the Human Abscess Isolate Streptococcus intermedius BA1.

Genome announcements

Planet PJ, Rampersaud R, Hymes SR, Whittier S, Della-Latta PA, Narechania A, Daugherty SC, Santana-Cruz I, Desalle R, Ravel J, Ratner AJ

Cigarette smoke increases Staphylococcus aureus biofilm formation via oxidative stress.

Infection and immunity

Kulkarni R, Antala S, Wang A, Amaral FE, Rampersaud R, Larussa SJ, Planet PJ, Ratner AJ

Retrocyclin inhibits Gardnerella vaginalis biofilm formation and toxin activity.

The Journal of antimicrobial chemotherapy

Hooven TA, Randis TM, Hymes SR, Rampersaud R, Ratner AJ

Microbiota of the upper and lower genital tract.

Seminars in fetal & neonatal medicine

Rampersaud R, Randis TM, Ratner AJ

Inerolysin, a cholesterol-dependent cytolysin produced by Lactobacillus iners.

Journal of bacteriology

Rampersaud R, Planet PJ, Randis TM, Kulkarni R, Aguilar JL, Lehrer RI, Ratner AJ

Cigarette smoke inhibits airway epithelial cell innate immune responses to bacteria.

Infection and immunity

Kulkarni R, Rampersaud R, Aguilar JL, Randis TM, Kreindler JL, Ratner AJ